N-Hydroxy Phthalimide (NHPI) – High-Purity Intermediate for API Manufacturing & Oxidation Processes
Product Description
PapChem Lifesciences supplies N-Hydroxy Phthalimide (NHPI) with ≥98% purity—widely used in pharmaceutical synthesis and oxidative transformations. Known for its performance and reliability, NHPI is a trusted choice for API manufacturers and CDMOs involved in complex chemical reactions.
🔍 Product Highlights
- Product Name: N-Hydroxy Phthalimide (NHPI)
- CAS Number: 524-38-9
- Chemical Formula: C₈H₅NO₃
- Molecular Weight: 163.13 g/mol
- Appearance: Pale yellow to white crystalline powder
- Purity: ≥98% (HPLC confirmed)
- Solubility: Soluble in ethanol, acetone, ether; limited in water
- Storage: Store in a cool, dry area in tightly sealed containers
- Grade: Pharmaceutical Intermediate / Industrial / Research
⚙️ Applications
- Oxidation Catalyst for API Synthesis
NHPI is widely used for mild and selective aerobic oxidation of alcohols, hydrocarbons, and intermediates—supporting cleaner, more efficient synthetic steps in pharmaceutical manufacturing. - Intermediate for API Production
Plays a key role in the synthesis of intermediates for active pharmaceutical ingredients (APIs), such as Amikacin and other aminoglycosides. - Nutraceutical & Natural Product Synthesis
Used in the development of complex molecules like Boswellic acid, known for its anti-inflammatory and therapeutic potential. - Therapeutic Research Applications
NHPI-based intermediates are being explored for their potential in managing chronic inflammatory conditions, as well as in oncology. - Support for CRAMS & CDMO Projects
Suitable for custom synthesis, redox control, and selective functionalization in multi-step pharma R&D and contract manufacturing projects.
📦 Packaging Options
- Bulk Packs: 5 kg | 25 kg HDPE drums with inner liner
- Custom Packaging: Available on request for pilot or commercial scale
- Shipping: Domestic and international delivery with regulatory compliance support
- Documentation: COA, MSDS, and stability data
🌐 Why Choose PapChem Lifesciences?
- Consistent ≥98% Purity – Every batch HPLC-tested for pharma-grade reliability
- Pharma-Ready – Used by global pharma and fine chemical manufacturers
- Documentation Support – COA, MSDS, and regulatory data supplied with every order
- GMP and ISO-Compliant Facilities – Ensuring high quality and traceability
- Scalable Supply – From lab development to commercial production
❓ FAQs
Q: Is NHPI suitable for regulated pharmaceutical applications?
A: Yes. Our NHPI meets the purity and documentation standards required for API synthesis and fine chemical manufacturing.
Q: Can I order in pilot or commercial volumes?
A: Absolutely. We support both R&D and commercial-scale sourcing needs with flexible packaging and documentation.
Q: Do you provide regulatory and QA documentation?
A: Yes. Each shipment includes COA and MSDS. Custom documentation support is also available.
